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PrAnimal studies only

Prostamax

Prostamax is a 4-amino-acid peptide (Lys-Glu-Asp-Pro) from a Russian research group. It has been tested in rat tissue cultures and in cells taken from older people. I found no treatment trial in people.

Not approved as a medicineLab studies only
OverviewDosingMixingResearchCommunitySafetyFAQSources

Prostamax quick reference

TypeTetrapeptide Lys-Glu-Asp-Pro (KEDP)
Studied forProstate tissue cultures, aging cell DNA
EvidenceCells and rat tissue only
RouteCommunity: injection
Half-lifeNot established

What is Prostamax?

Four-amino-acid peptide from a Russian research group.

Marketed for prostate health; no human treatment trial exists.

Not the same as animal prostate extracts such as Prostatilen.

How Prostamax works

Tissue culture

0.05 ng/mL stimulated growth in rat prostate explants (young and old).

Chromatin loosening

In cells from people aged 75–86 it loosened tightly packed DNA.

Older-adult lymphocytes

In a 2004 test, it opened chromosome 1 chromatin in cells from people aged 75–88.

What Prostamax is studied for

Lab / cellsProstate tissue culture

Rat prostate explants grew more at a very low concentration.

Lab / cellsChromosome markers

Cells from people aged 75–86 showed altered chromosome markers.

Lab / cellsOlder-adult blood cells

Prostamax loosened chromosome 1 chromatin in lymphocytes (2004).

PeopleProstate symptoms in people

No treatment trial found.

Prostamax dosing protocol

ItemWhat the sources show
Human doseNot established
Studied inRat tissue cultures and cultured cells from older people

Prostamax is not the same as Prostatilen, a prostate extract product that the Russian group lists separately in its clinical review. ClinicalTrials.gov lists no Prostamax trial (searched 5 Nov 2026).

HUMAN DOSENone existsTrial
COMMUNITY RANGE500–1,000 mcg dailyCommunity
COMMUNITY CYCLE10–20 daysCommunity

Label and trial amounts come from the sources below. Community amounts are what people report; they have not been tested.

Mixing

Vial10 mg
+
BAC water2 mL
=
Strength5 mg per mL

Example math only. At 5 mg per mL, 1 mg = 0.2 mL.

Open the peptide calculator

What the research found

No treatment results in people exist. Lab findings:

0.05 ng/mLConcentration that stimulated growth in rat prostate tissue cultures (young and old rats)
CellsIn cells from people aged 75 to 86, it changed chromosome markers; the authors say this may switch on silenced genes

Adv Gerontol 2006 (PMID 17152728); Georgian Med News 2012 (PMID 23221144).

Prostamax community experience

What users report. Not tested in trials.

Positive reports

  • Better flow Some report a stronger stream or less hesitancy.
  • Fewer night trips A few get up less at night.
  • Less pelvic pressure Some feel more complete emptying.

Negative & mixed

  • Nothing changed Many notice no difference.
  • No numbers PSA, volume and flow data are rarely shared.
  • Side complaints Injection irritation, headache or tiredness in some reports.

Prostamax stacking

Prostamax + Vesilute

Prostate-and-bladder bioregulator pairing. Untested.

Prostamax + prostate drugs

Alpha blockers and 5-ARIs change symptoms and PSA readings.

Prostamax + TRT

Testosterone changes prostate monitoring; tell the prescriber.

Prostamax side effects & safety

Common

  • No human safety data exists.
  • Injection-site redness or bruising (community).
  • Headache or tiredness (community).
  • Dizziness or nausea now and then (community).

Less common

  • Changes in urinary feel (community).
  • Effects on PSA, hormones and fertility: unknown.
  • Safety with kidney impairment or blockage: unknown.

Precautions

  • Avoid with known or suspected prostate cancer or high PSA.
  • Retention, fever or blood in urine need a doctor first.
  • Prostate drugs or TRT: tell the clinician; PSA readings change.
  • Blood thinners raise injection bruising.
  • Avoid with peptide or vial-ingredient allergy.

Our verdict on Prostamax

Lab and tissue-culture evidence only. No human prostate outcome has been tested.

Prostamax FAQ

Does Prostamax help the prostate?

No human trial exists. Evidence is rat tissue culture and cell work.

Is Prostamax the same as Prostatilen?

No. Prostatilen is a prostate extract; Prostamax is a defined peptide.

Will it change PSA?

Unknown. Never measured in people.

Is Prostamax approved?

No. Not approved as a medicine.

Sources

  • Tissue-specific effect of synthetic peptides in organotypic culture. Adv Gerontol 2006, PMID 17152728
  • Deheterochromatinization in old age induced by Prostamax. Georgian Med News 2012, PMID 23221144
  • Khavinson VKh, Kuznik BI, Ryzhak GA. Adv Gerontol 2014 (clinical review; lists Prostatilen, not Prostamax)
  • ClinicalTrials.gov search by intervention name, run 5 Nov 2026: 0 results
  • Effects of short peptides on lymphocyte chromatin in senile subjects (Vilon, Epithalon, Livagen, Prostamax, Cortagen). Bull Exp Biol Med 2004, PMID 15085253
  • Community reports summarised from public peptide-community notes (peptideprotocols.app page); user reports, not research